Vitamin B12 plays a fundamental role in cellular reprogramming and tissue regeneration, being a nutrient obtained from foods such as fish, red or white meat, eggs, milk and other dairy products, a study revealed.
The work, led by the biomedical research institute IRB Barcelona and published this Thursday in the journal Nature Metabolism, focused on investigating the role of B12 in cellular reprogramming, a process that is considered to mimic the first phases of bone repair. fabrics.
With the data on the table, the IRB Barcelona team, led by Manuel Serrano, discovered that cellular reprogramming in mice consumes large amounts of vitamin B12, and that its decrease becomes a limiting factor that delays and harms some aspects of the rescheduling process.
Vitamin B12 is a well-known micronutrient that has long been valued for its essential role in maintaining nerve function, contributing to the production of red blood cells and facilitating DNA synthesis, all vital processes for overall health.
Considering the abundance of vitamin B12 in the mice’s normal diet, the researchers were surprised to observe that a B12 supplement significantly improved the efficiency of reprogramming.
The researchers also observed that intestinal cells that initiate repair undergo a process similar to cellular reprogramming and that they also benefit from vitamin supplementation.
“These results are promising for regenerative medicine, with the potential to benefit patients through better nutrition,” highlighted Manuel Serrano.
The study also investigated the metabolic requirements of cellular reprogramming and found that vitamin B12 is a limiting factor in a branch of metabolism involved in a reaction known as methylation.
For cellular DNA to initiate tissue reprogramming or repair, high levels of methylation reaction and, therefore, vitamin B12 are required.
Without sufficient levels of vitamin B12 in the processes of cell reprogramming or tissue regeneration, multiple errors in genetic function are caused.
Source: TSF
